11/18/2012

Antihypertensive drugs and sexual function

Ask about: some, 38 years old, from Wenzhou, hypertension, primary diastolic blood pressure high, generally at about 140/100mmHg, since taking hypotensor amlodipine or Adalat appeared after impotence (ED), and the use of antihypertensive drugs on ask this? How to treat?

Answer : the emergence of male sexual dysfunction due to many reasons, such as cardiovascular disease, type 2 diabetes, hypertension itself also can cause ED, but after taking antihypertensive drugs in ED is not rare. According to the statistics of hypertension not taking antihypertensive drugs the occurrence rate of ED is 15%, and the essential hypertensive patients taking antihypertensive drugs after the onset of ED 35%. Finland University of Tampere Shiri study of 2510 mail questionnaires shows that: the application of calcium channel blockers, angiotensin II receptor antagonists, non selectiveßblockers or diuretics increase the ED risk. But with nitrate drugs, angiotensin-converting enzyme inhibitors, selective beta blocker and lipid-lowering drugs without correlation.

Features include sexual desire, erection and ejaculation in three aspects. As a result of antihypertensive drug classes, more varieties, their functional inhibition mechanism, link and to varying degrees, the probability of the occurrence of different from 4%-30%. Effect on sexual function is the largestß - blocker ( propranolol ), followed by ( diuretics hydrochlorothiazide ), calcium blockers ( nifedipine ). Interesting only in angiotensin II receptor antagonists in Stan on sexual function in the erectile, sexual desire and ejaculation three party has not reduced and improved.

In this case the sexual dysfunction may be associated with the use of antihypertensive drugs, because of Norvasc and Adalat are calcium channel blockers, suggested that the cases of disabled. Use of angiotensin converting enzyme inhibitor benazepril or angiotensinⅡ receptor antagonist valsartan ( Diovan). Such as single agent antihypertensive effect is not good, can try to selectiveß - blocker bisoprolol ( Kang Xin ), because the latter on the reduction of diastolic blood pressure.



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