11/27/2012

Hypertension should be how to treat?

One, general treatment: hypertension and central nerve functional disturbance, should pay attention to work and rest.

Two, antihypertensive drug treatment.

( a ) angiotensin converting enzyme inhibitors : current application of captopril, enalapril.

( two): calcium antagonists are a group of different chemical structure, mechanism of action are not the same as the drug. Due to the inhibition of calcium ions through the cell membrane calcium channel flow, thus known as calcium channel antagonists. Commonly used drugs with verapamil, diltiazem and nifedipine, nitrendipine.

( three): direct vasodilators relax vascular smooth muscle, the expansion of blood vessels, reduce blood pressure. Drugs commonly used: 1 snp. 2 minoxidil. 3 hydralazine.

( four) effects on sympathetic nervous system of antihypertensive drugs.

1 central fucked sympathetic inhibitors: ( 1) clonidine. ( 2) methyl dopa.

2 sympathetic ganglion blockers. Often have a special, for the treatment of hypertensive encephalopathy.

3 sympathetic postganglionic blocker. The sympathetic nerve endings in the storage of noradrenaline depletion, and reached the purpose of reducing blood pressure. Commonly used drugs are: ( 1) guanethidine. ( 2) reserpine.

4 adrenergic receptor blocker.

( 1)βreceptor blocker; Liu Anbian heart is WHO recommended antihypertensive agents. Acebutolol.

( 2) alpha blockers: commonly used with prazosin. Doxazosin.

( five) diuretic hypotensive drugs.

1 thiazide: is the most widely used oral diuretic antihypertensive agents, hydrochlorothiazide.

2 chlorthalidone.

3 furosemide.

4 triamterene.



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