2010 Chinese hypertension prevention guide points out that, as the two levels of prevention, the patients should be: (1 ) the use of aspirin in hypertensive patients with stable coronary heart disease, myocardial infarction, ischemic stroke or TIA history and peripheral atherosclerotic disease patients, requiring application of low-dose aspirin ( 100 mg/d ). ( 2) combined with acute attacks such as thrombosis in acute coronary syndrome, ischemic stroke or TIA, occlusive peripheral atherosclerosis, according to the relevant guidelines recommend the use of aspirin, usually in the acute period can give load agent ( 300 mg/d ), and then the application of low dose ( 100 mg/d ).
As a primary prevention: ( 1) essential hypertension complicated with atrial fibrillation in patients with high risk of oral anticoagulants such as warfarin should be used, or not used in patients on oral anticoagulant; ( 2) hypertensive patients with diabetes, cardiovascular high risk by low-dose aspirin ( 75mg-100mg/d ).
Not all blood pressure patients to take aspirin. For low-risk patients taking aspirin, the benefits of which bear little bleeding risk, and high risk patients can obtain larger net benefit.
In addition, not all blood pressure patients can safely use aspirin. The combined activity of gastric ulcer, severe liver disease, hemorrhagic disease should be used carefully. Therefore, response or the necessary screening, there are no incidence of gastrointestinal hemorrhage risk factors, such as gastrointestinal disease ( ulcer disease and its complications History), 65 years of age or older, while taking corticosteroids or other anticoagulants or non-steroidal anti-inflammatory drugs. If there is a high risk factors preventive measures should be taken, including screening and treatment of Helicobacter pylori infection, prophylactic use of proton pump inhibitors.
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