Renin - angiotensin system is one of the mechanisms of blood pressure control. Study finds, angiotensin II can be directly systolic systemic small vessels, indirectly cause the body sodium and water retention, leading to high blood pressure. In addition, angiotensin II injury of the peripheral arteriole intima, the hyperplasia of vascular smooth muscle, leading to heart, brain, kidney and other organs damage.
Hypertension patients mostly to long-term medication, should pay attention to is, the medication should not only make the drop in blood pressure or is close to the normal range, but don't forget to pay attention to the heart, brain, kidney protection.
In recent years in the treatment of hypertension in progress, is the renin - angiotensin system discovery and research. At present the confirmation, the renin - angiotensin system is one of the mechanisms of blood pressure control. Study finds, angiotensin II can be directly systolic systemic small vessels, indirectly cause the body sodium and water retention, leading to high blood pressure. In addition, angiotensin II injury of the peripheral arteriole intima, the hyperplasia of vascular smooth muscle, leading to heart, brain, kidney and other organs damage, eventually there will be a cardiac enlargement, heart failure, stroke, renal failure and other life-threatening complications. The renin angiotensin system results and consequent hypertension treatment breakthrough is of great significance.
Angiotensin converting enzyme inhibitors ( ACEI ) in the treatment of hypertension plays a very important role, it can inhibit angiotensin converting enzyme catalysis, the angiotensin II levels drop, action to reduce or disappear, so that the peripheral arteriolar dilation, and decreased blood pressure, protect the heart, brain, kidneys and other organs.
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